NLPhD: RSV Infection and Immunity, Replacing Animal Models
Netherlands Government, National Institute for Public Health and the Environment (RIVM)Netherlands
Global health and wellbeingGlobal health and infectious diseaseResearchData
Why this is on the board
Research into vaccines against RSV, a virus that makes many babies and older people seriously ill, still relies heavily on laboratory animals and on cell lines that bear little resemblance to real airways. You standardise a model of human airway cells together with regulators in the United Kingdom and Germany, so that it can become a recognised method that other labs and vaccine makers adopt. That way your work reaches beyond a single PhD thesis.
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About the role
Four-year PhD research developing and standardising human cell-based models to evaluate RSV immunity and reduce animal testing in vaccine research. - Co-design standardisation protocols for RSV neutralisation models with European regulatory partners and transfer methodology across sites. - Perform cell culture work, viral infections, microscopy, sequencing, and immunoassays to advance the model and explore population variability. - Analyse data, publish peer-reviewed findings, present at conf…
More about Netherlands Government, National Institute for Public Health and the Environment (RIVM)Why this problemGlossary
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